Scientists at the University of Glasgow have developed a new machine learning model to translate the language of proteins using a powerful supercomputer.
The cross-disciplinary team created a large language model (LLM) called PLM-Interact to better understand protein interactions and predict which mutations will impact how these molecules interact with each other.
Early tests of PLM-Interact show that it outperforms competing models in understanding and predicting how proteins interact with one another.
The study, published in Nature Communications, demonstrates the potential of PLM-Interact in advancing our understanding of protein interactions.
Author's summary: Scientists use AI to understand protein language.