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Scientists Use AI to Learn the Language of Biomolecules

Scientists at the University of Glasgow have developed a new machine learning model to translate the language of proteins using a powerful supercomputer.

The cross-disciplinary team created a large language model (LLM) called PLM-Interact to better understand protein interactions and predict which mutations will impact how these molecules interact with each other.

Early tests of PLM-Interact show that it outperforms competing models in understanding and predicting how proteins interact with one another.

The study, published in Nature Communications, demonstrates the potential of PLM-Interact in advancing our understanding of protein interactions.

Author's summary: Scientists use AI to understand protein language.

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University of Glasgow University of Glasgow — 2025-10-27

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